Healthcare Providers


Any institution within the National Cancer Institute's National Clinical Trials Network (NCTN) may open the Lung-MAP study at their site.  Learn more about the protocol at or by contacting one of the Lung-MAP protocol coordinators:

Jennifer Beeler
SWOG | Cancer Research Network
Operations Office
Lung-MAP Project Manager | Protocol Project Manager, SWOG
4201 Medical Drive #250  |  San Antonio, TX  78229
Ph: 210.614.8808, Ext 1026 |

Melissa Biddle
SWOG | Cancer Research Network
Operations Office
Lung-MAP Project Manager | Protocol Project Manager, SWOG
4201 Medical Drive #250  |  San Antonio, TX  78229
Ph: 210.614.8808, Ext 1015 |

Looking for the study protocol and other resources for institutions opening Lung-MAP?  You can find them at: CTSU website members section

Click HERE for the most recent Lung-MAP newsletter.

Some aspects of the trial have undergone revision. Click HERE for a full trial schema.

What are the main objectives of Lung-MAP?

A primary objective of Lung-MAP trial sub-studies is to learn whether targeted cancer therapies that are matched to the genomic makeup of a patients’ lung cancer tumors are more effective than the current standard therapies in halting or reversing the progress of the disease and in extending the patient’s life.
A key part of the Lung-MAP trial is that it will screen a large  population of patient volunteers with lung cancer and evaluate the genetic characteristics of their tumors.  Based on these genomic profile results, each eligible patient will be assigned to Lung-MAP in one of two ways. They will either make a genomic “match” to a sub-study testing an investigational drug, or be added to a non-match sub-study that offers an immunotherapy combination.

What are Lung-MAP’s secondary objectives?

Researchers on each trial sub-study will also evaluate tumor response rates and the frequency and severity of side effects patients experience.

The National Cancer Institute will store tumor and blood samples from patients enrolled in the trial for future exploratory research on squamous cell lung cancer.

What are the benefits of the Lung-MAP approach to cancer research?

  • Enrollment efficiency:  A single test that looks at >200 cancer-related genes for genomic alterations that will help match patients to multiple trial sub-studies is more efficient than a separate screening process for each trial.
  • Operational efficiency:  A single “master protocol” can be amended as needed as drugs enter and exit the trial, rather than developing and launching a separate protocol for each new drug.
  • Predictability:  If a drug meets predetermined efficacy and safety criteria, the drug and its accompanying diagnostic biomarker will be eligible for FDA approval.

Who is conducting the Lung-MAP trial?

The trial will open at a network of cancer centers, community hospitals, academic medical centers, and physician cooperatives across the United States with operations being managed by SWOG Cancer Research Network within the National Cancer Institute’s National Clinical Trials Network. 

Where can I learn more about Lung-MAP?

As more detailed information about the trial becomes available, it will be summarized on this website.



Genomic profile screening

Patients are screened using a comprehensive genomic profiling platform that looks at over 200 cancer-related genes for genomic alterations.


Sub-study Assignment

Based on the results of this screening, patients are assigned to whichever sub-studies testing different investigational treatments best suits their genomic profile. If a patient's genetic profile does not match one of the targeted treatment sub-studies, they will be assigned to a non-match substudy. 


Innovative Approach

This innovative approach improves a patient’s likelihood of receiving a drug targeted at the genetic profile of their particular tumor while allowing for new therapies in development to be added as the trial progresses.